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Neomycin - Neomycin is one of the more toxic aminoglycosides IF used systemically. (so it is not given by injection)
- Neomycin is contained in single “poly-antibiotic” preparations for topical use (wound ointments, irrigants, etc.)
- Neomycin is used primarily for oral therapy. As there is little absorption, it is really local therapy.
- There is evidence that very small amounts of oral Neomycin are absorbed and cause residues. In fact, you can produce residues in the kidneys without producing detectable concentrations in the bloodstream.
