The tetracyclines are used to treat both systemic and local infections. General organ infections include bronchopneumonia, bacterial enteritis, urinary tract infections, cholangitis, metritis, mastitis, prostatitis, and pyodermatitis. Specific conditions include infectious keratoconjunctivitis in cattle, chlamydiosis, heartwater, anaplasmosis, actinomycosis, actinobacillosis, nocardiosis (especially minocycline), ehrlichiosis (especially doxycycline), eperythrozoonosis, and haemobartonellosis. Minocycline and doxycycline are often effective to a somewhat lesser degree against resistant strains of Staphylococcus aureus.