The sulfonamides are commonly used to treat or prevent acute systemic or local infections.

 

Disease syndromes treated with sulfonamides include actinobacillosis, coccidiosis, mastitis, metritis, colibacillosis, pododermatitis, polyarthritis, respiratory infections, and toxoplasmosis.

 

Sulfonamides are more effective when administered early in the course of a disease. Chronic infections, particularly with large amounts of exudate or tissue debris present, often are not responsive.