ANTIMICROBIAL ACTIVITY

 

Antimicrobial activit2
Antimicrobial activit2

Mode of Action

Chloramphenicol and its congeners inhibit microbial protein synthesis by binding to the 50S subunit of the 70S ribosome and impairing peptidyl transferase activity.

The effect is usually bacteriostatic but, at high concentrations, chloramphenicol may be bactericidal for some species.

 

 

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