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| Quinolone | Species | Dosage, Route, and Frequency |
| Nalidixic acid | Cats, dogs | 3 mg/kg, PO, qid |
| Enrofloxacin | Cats | 5 mg/kg, PO, sid-bid |
| Dogs | 5-20 mg/kg, PO, sid-bid
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| 2.5 mg/kg, SC, once then PO | ||
| Beef cattle (not veal or dairy) | 7.5-12.5 mg/kg, SC, once
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| 2.5-5 mg/kg, SC, sid | ||
| Pigs | 2.5-5 mg/kg, PO or IM, sid | |
| Preruminant calves | 2.5-5 mg/kg, PO or SC, sid | |
| Marbofloxacin | Cats, dogs | 2.75-5.5 mg/kg, PO, sid |
| Difloxacin | Dogs | 5-10 mg/kg, PO, sid |
| Orbifloxacin | Cats, dogs | 2.5-7.5 mg/kg, PO, sid |
