|
|
Dogs: 10-60 mg/kg, PO, TID | 90-120 min | <24 hr | Probably ineffective due to very short half-life; liver toxicity and pancreatitis. | ||||
| Zonisamide | Dogs: 4-8 mg/icg/day, hr days PO, divided; up to 10 mg/kg. bid | 15-20 hr | 3-4 days | 10-40 mg/L (45-180 mmol/L) | Sedation, ataxia, loss of appetite | |||
| Tranquilizers and Sedatives | ||||||||
| Dosage | ||||||||
| Drug | Dogs | Cats | Ferrets | Rabbits | Horses | Cattle | Pigs | |
| Benzodiazepines | ||||||||
| Diazepam | 1 mg/ka, IV or PO | 1 mg/kg,
IV |
2 mg/kg,
IM |
2 mg/kg, IV; 5-10
mg/kg, IM or IP
|
0.05-0.4 mg/kg, IV | 0.5- 1.5 mg/kg, IV | 0.5-10
mg/kg, IM; 0.5-1.5 mg/kg, IV |
|
| Midazolam | 2 mg/kg,
IM or IV |
|||||||
| Butyrophenone | ||||||||
| Azaperone | 0.4-0.8
mg/kg, IM |
2.2 mg/kg,
IM |
||||||
| Phenothiazines | ||||||||
| Acepromazine maleate | 0.05-0.1 mg/kg, IV, IM, or SC; 0.55-2.2 mg/kg, PO, TID- QID | 0.11- 0.22 mg/kg, IV,IM, or SC: 1.1-2.2 mg/kg, PO,BID-
TID |
0.1-
0.25 mg/kg, IM or SC |
1-5
mg/kg, IM |
0.04-0.1
mg/kg, IV, IM, SC, or PO, StD |
0.05-0.1 mg/kg, IV, IM, or SC | 0.1-0.2 mg/kg, IV, IM, or SC | |
| Chlorpromazine hydrochloride | 0.55-4.4 mg/kg,
IV; 1.1- 6.6 mgkg, IM; 3.2 mg/kg, PO, TID- QIDas needed |
1-2 mg/kg, IV or IM, BID | 3 mg/kg. (may
produce myositis) |
0.5-4.0 mg/kg, IM | ||||
| Promazine | 2-6 | 2-4.4 | 0.4-1 mg/kg. | 0.4-1 | 0.4-1 | |||
