Antibiotics
Interactions
The absorption of tetracyclines from the Gl tract is decreased by milk and milk products (less so for doxycycline and minocycline), antacids, kaolin, and iron preparations
Withdrawal time:
| Drug Withdrawal and Milk Discard Times of Tetracyclines | ||
| Tetracycline | Species | Withdrawal Time (days) |
| Oxytetracycline3 | Cattle | 15-22 |
| Pigs | 22 | |
| Poultry | 5 | |
| Oxytetracycline (long-acting)3 | Cattle | 28 |
| Chlortetracycline | Cattle | 10 |
| Pigs | 1-7 | |
| a Not for use in lactating dairy cows | ||
Activity profile: Chlortetracycline, Oxytetracycline, Tetracycline, Doxycycline
Good Gram (+) aerobes: Bacillus, Corynebacterium sp., E. rhusiopathiae, L. monocytogenes, Streptococci. Gram (-)
bacteria: Actinobacillus, Bordetella,Brucella, F. tularensis, Haemophilus,
- multocida, Yersinia, Campylobacter fetus, Borrelia, Leptospira Anaerobic
bacteria: Actinomyces, Fusobacterium. Also -.Mycoplasma, Chlamydia sp. (including C. psittaci), Rickettsia sp., (inluding C. burnetii, Ehrlichia sp., and Anaplasma) certain protozoa (Entamoeba, Plasmodium).
Resistant Constitutive: some Mycobacterium sp., P. vulgaris, P. aeruginosa, Serratia Acquired: staphylococci, enterococci, Enterobacteriaceae. Anaerobes such asBacteroides, and Clostridium, some Mycoplasma (M. bovis, M. hyopneumoniae are resistant)
