![Highly soluble sulfonamides used for urinary tract infections](https://xn--mgbaaebccr4cxezfcdfg0g.com/storage/2018/04/Highly-Soluble-Sulfonamides-Used-for-Urinary-Tract-Infections.jpg)
A few very water-soluble sulfonamides, eg, sulfi-soxazole (sulfafurazole) and sulfasomidine, are rapidly excreted via the urinary tract (>90% in 24 hr) mostly in an unchanged form; because of this, they are primarily used for the treatment of urinary tract infections.
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