|
|||||||
| Methocarbamol | Dogs, cats: 44 mg/kg, IV^up to 330 mg/kg/day for tetanus or strychnine poisoning; 132 mg/kg/day, PO, divided bid-tid Horses: 4.4-55 mg/kg, IV | ||||||
| Guaifenesin | Dogs: 44-88 mg/kg, IV Horses, ruminants: 66-132 mg/kg, IV | ||||||
| Diazepam | Cats: 2-5 mg, PO, TID, for urethral obstruction | ||||||
| Dantrolene | Horses: 15-25 mg/kg, slow IV, QID; 2 mg/kg, PO, SID, for pre\ ention of exertional rhabdomyolysis Swine: 3.5 mg/kg, IV | ||||||
| Phenytoin | Horses: 6-8 mg/kg, PO, SID, increase by 1 mg/kg every 3 days until
rhabdomyolysis is prevented or the horse appears sedated |
||||||
| Anabolic Steroids | |||||||
| Drug | Dosage | ||||||
| Boldenone undecylenate | Horses: 1.1 mg/kg, IM, every 3 wk | ||||||
| Nandrolone decanoate | Dogs: 1-5 mg/kg IM, once/wkCats: 10-20 mg, IM, once/wk | ||||||
| Stanozolol | Dogs: 1-4 mg, PO, bid; 25-50 mg, deep IM, once/wk Cats: 1-2 mg PO, BID; 25 mg, deep IM, once/wk Horses: 0.55 mg/kg, deep IM, once/wk | ||||||
| Aoticonvulsants Drugs | |||||||
| Anticonvulsaut Drug | Dosage and
Frequency |
Half-life | Time to Steady State | Time Therapeutic Level | Adverse
Effects/Comments |
||
| First-line Anticonvulsant Drugs | |||||||
| Phenobarbital | Dogs: 2-4
mg/kg, PO,BID (startin g dose); up to 10 mg/kg, BID |
40-90
hr (Beagle s 25-38 hr)
|
10-24 days | 15-45 mg/mL (66-200
mmol/L), preferably keep values within 20-35 mg/mL (85-150 mmol/L) |
Sedation,
polydipsia, induces P450 system, increase in liver enzymes; liver disease is uncommon. Adjust dosage by monitoring serum levels.
|
||
| Cats: 1-2
mg/kg. PO.BID (startin g dose) Horses: 3-5 mg/kg. |
34-43
hr 18 hr 13 hr
|
10-30 mg/mL 10-40
mg/ml (43-175 mmol/L)
|
Liver enzymes do not increase in
cats. Adjust dose in all species by monitoring serum |
||||
